Shy Drager Syndrome, also known as multiple system atrophy (MSA), is a rare neurodegenerative disorder that affects the autonomic nervous system. While the term Shy Drager Syndrome is widely recognized, it has been replaced with the more specific term MSA. The change in nomenclature reflects the need for a more inclusive diagnosis, as the previous term focused primarily on one aspect of the condition. Other synonymous terms commonly used include olivopontocerebellar atrophy, sporadic adult-onset ataxia, and autonomic failure. These synonyms help encompass the diverse symptoms observed in MSA patients, ranging from motor impairment to autonomic dysfunction. Recognizing and utilizing these synonyms helps to broaden awareness and understanding of this complex syndrome.