Often, we get tired of using the same old phrases again and again. "Sick and tired of" is one such phrase which has been used for ages. It is used to express one's frustration or displeasure with something. If you are looking for a fresh and new way of saying this, here are some synonyms that might help: weary of, fed up with, bored stiff, jaded with, wearied by, exasperated with, aggrieved of, and tired of. Giving a variety of words to express your frustration can add a fantastic element to your conversation or writing.