The Simple Clinical Colitis Activity Index (SCCAI) is a tool used to assess the severity of ulcerative colitis, a chronic inflammatory bowel disease. Synonyms for the SCCAI include the Mayo Clinic score, the Ulcerative Colitis Disease Activity Index, and the Clinical Disease Activity Index. These tools use various criteria such as stool frequency, rectal bleeding, and physician assessment to determine disease activity and guide treatment decisions. The SCCAI and its synonymous forms are essential in monitoring the disease's progression and response to treatment. Health care professionals use the SCCAI in combination with laboratory testing and imaging studies to ensure proper management of ulcerative colitis.