Splicing-dependent gene expression refers to the process in which a gene is transcribed and translated into a protein based on the specific splicing pattern of the mRNA. Synonyms for this term include transcript isoform expression, alternative splicing-mediated gene expression, and exon utilization-dependent gene expression. The term alternative splicing, which refers to the process by which multiple distinct mRNA transcripts can be generated from a single gene, is also often used in reference to splicing-dependent gene expression. Additionally, terms such as splice variant-specific gene expression and mRNA splicing pattern-dependent gene expression can also be used to describe this process. These synonyms help to clarify the complex genetic mechanisms involved in gene expression and highlight the importance of splicing in regulating protein diversity and function.