Split genes, or more accurately spliced genes, are those which contain multiple segments or exons that are separated by introns. When these segments are spliced together, they form the final messenger RNA or mature transcript. Synonyms for split genes include spliced genes, processed genes, and alternatively spliced genes. Additionally, there are several terms that relate to specific splicing events such as alternative splicing, differential splicing, and cryptic splicing. These terms refer to the different ways in which exons and introns can be arranged, resulting in a variety of mRNA isoforms with varying functions and properties. Understanding these alternatives splicing mechanisms is essential for understanding gene expression and regulation.