Spongy Degeneration of Infancy, also known as Canavan disease, is a rare genetic disorder that affects the white matter of the brain. This debilitating condition leads to the progressive destruction of myelin, the substance necessary for proper nerve function. As the disease progresses, individuals may experience developmental delays, muscle weakness, and intellectual disabilities. Although its name may sound daunting, understanding synonyms for Canavan disease can help to shed light on this condition. Synonyms for Spongy Degeneration of Infancy include Canavan-Van Bogaert-Bertrand disease, Canavan-Van Bogaert-Zeman syndrome, and Aspartoacylase deficiency. Although synonyms may differ, the underlying fact remains the same: early detection and treatment are crucial for managing the effects of this rare disorder.