Striatonigral degeneration is a medical condition caused by the degeneration of some neurons in the brain, which results in a gradual loss of control of body movements. Some synonyms for it include Parkinsonism, Parkinson's disease, or Parkinson's syndrome, as well as Multiple System Atrophy (MSA). Other less common synonyms include Progressive Supranuclear Palsy (PSP), Shy-Drager Syndrome, and Olivopontocerebellar Atrophy (OPCA). While these medical conditions differ in the location and severity of the damage in the brain, they all lead to motor problems and can cause damage to the autonomic nervous system. Treatment options include medication, lifestyle changes, and surgery, depending on the symptoms and the progression of the disease.