The submandibular fossa is a depression located on the internal surface of the mandible bone, bordered by the mylohyoid line and the mandibular symphysis. Synonyms for this term include the mandibular gland fossa, submaxillary fossa, and the submandibular gland fossa. This depression provides housing for the submandibular gland, the tongue, and their respective ducts. This gland secretes saliva, which plays a vital role in digestion. The submandibular gland fossa is an essential anatomical feature, and understanding its location and function is crucial in determining the cause and treatment of any disorder or disease related to it.