Systemic Lupus Erythematosus, commonly known as Lupus, is a chronic autoimmune disease that affects multiple organs and tissues in the body. There are several synonyms for Lupus that are used interchangeably in medical literature and discussions. Some of the commonly used synonyms include SLE, Lupus erythematosus disseminatus, Lupus disseminatus, and systemic lupus. The term "systemic" refers to the fact that Lupus can impact multiple systems of the body, including joints, skin, kidneys, and the nervous system. It is important to note that while the different terminologies may be used interchangeably, the symptoms and treatment for Lupus remain the same. Individuals diagnosed with Lupus should work closely with their healthcare provider to manage their symptoms and maintain optimal health.