To take the bite out of something means to make it less unpleasant or harmful. Antonyms for this phrase would include increasing the harshness or severity of something. For example, to enhance the bitterness, wrath or severity of an experience would be an opposite variation of the expression 'taking the bite out of'. Alternately, another antonym for 'take the bite out of' could be to intensify or aggravate an existing situation, causing it to become more challenging, difficult, or uncomfortable. In essence, any opposite action that aggravates, intensifies, or worsens something would serve as an antonym for the phrase 'take the bite out of.