The phrase "the rub" can be used to describe a difficulty, complication or challenge that arises in a particular situation. There are several synonyms that can be used in place of this phrase. For instance, you could say that there is a snag, hitch or obstacle in your plans. Alternatively, you could describe the situation as a dilemma or complication. If you want to emphasize the frustration or annoyance caused by the problem, you could use terms like hassle, nuisance or inconvenience. Ultimately, there are many different ways to convey the idea of a challenge or difficulty, but each of these synonyms provides a slightly different shade of meaning that can help you communicate more effectively.