Thiazides are a family of diuretic drugs used to treat high blood pressure and fluid accumulation. Some synonyms for thiazides are thiazide diuretics, thiazide-type diuretics, and sulfonamide diuretics. These drugs work by inhibiting the reabsorption of sodium and chloride ions in the kidney tubules, leading to increased water and electrolyte excretion. Some commonly prescribed thiazides include hydrochlorothiazide, chlorthalidone, and indapamide. Thiazides are usually well-tolerated, but like all medications, they can have side effects, such as dehydration, electrolyte imbalances, and low blood pressure. It is important to follow your healthcare provider's instructions when taking thiazides.