Thrombophilia is a medical condition involving increased risk of blood clots. It is caused by a genetic mutation or acquired disorder that increases clotting factors in the bloodstream. Synonyms for thrombophilia include hypercoagulability, clotting disorder, hyperthrombotic state, prothrombotic condition, and thrombotic tendency. Blood clots pose risks such as deep vein thrombosis (DVT), pulmonary embolism (PE) and stroke, which could be fatal. Therefore, it is important to manage thrombophilia by reducing thrombotic risk factors like smoking, obesity, contraceptive pills, and long periods of immobility. Treatment options for thrombophilia include the use of anticoagulants, aspirin, and compression stockings, as well as lifestyle changes such as regular exercise and maintaining a healthy diet.