Antonyms for "throw in lot with" include words such as "dissociate," "disband," "separate," and "disunite." These words suggest a breaking apart and a lack of unity or partnership. They indicate a rejection of the idea of joining forces or aligning with a particular group or individual. Instead, they imply independence, detachment, and a refusal to be swayed by the influence of others. The opposite of "throw in lot with" is to stand alone, to distance oneself from others, and to prioritize personal values and beliefs over any alliance or agreement with someone else.