"Time and time again" refers to something that happens repeatedly or consistently. There are various synonyms that can be used instead of this phrase, including "repeatedly," "frequently," "often," "consistently," "continuously," "regularly," "persistently," and "redundantly." These words convey the same meaning as "time and time again" and can be used interchangeably. However, depending on the context of the sentence or the situation, certain synonyms may be more appropriate than others. Regardless, using synonyms can help diversify one's writing and make it more engaging to readers.