Tissue plasminogen activator, or tPA for short, is a well-known drug that is used to dissolve blood clots in patients suffering from conditions such as heart attacks or strokes. However, there are many other terms that can be used to describe this medication, including alteplase, rtPA, and activase. All of these names refer to the same medication, but they may be used by different manufacturers or in different countries. As a healthcare provider, it is important to be aware of these different synonyms for tPA so that you can communicate effectively with your colleagues and provide the best possible care to your patients.