Topiramate is a medication used to treat seizures and prevent migraine headaches. Other words commonly used to refer to this drug include Topamax, Topiragen, and Qudexy XR. While all of these words are technically brand names for forms of topiramate, they are often used interchangeably with the generic name. Topiramate belongs to a class of drugs called anticonvulsants or anti-seizure medications. It works by reducing abnormal brain activity that causes seizures or migraines. This medication may also be prescribed for off-label uses, such as treating bipolar disorder or obesity. If you have been prescribed topiramate, it is important to take it exactly as directed by your healthcare provider.