The word "un-easiest" is a comparative form of "uneasy," which means not comfortable, relaxed, or calm. Therefore, its antonyms could include words like comfortable, easy, agreeable, calm, peaceful, contented, relaxed, and unperturbed. These words describe the opposite feeling of discomfort and anxiety, which "un-easiest" tends to convey. Using antonyms in writing or speech could help to create a more positive and uplifting message, especially when the topic or context involves negative emotions. For instance, one could say "the easiest thing to do is to relax and enjoy the moment," which directly opposes the idea of being uneasy or anxious.