Unfetters is a verb that means to release or free from constraints or restrictions. There are several synonyms that could be used in place of unfetters, depending on the context and tone of the sentence. For example, unshackles, disentangles, liberates, emancipates, and unburdens could all be substituted for unfetters. Each of these words connotes a sense of liberation or freedom from something that was previously hindering or restricting. Whether it's freeing oneself from physical or mental constraints, each of these synonyms effectively communicates a sense of release and empowerment.