Applejohn and upJohn are corruptions of Ap-john.
"The Romance of Names"
Ernest Weekley
At any rate, when such occasions were imminent, Mrs. upJohn was wont to summon the dressmaker to come to her house, and the dressmaker would come promptly and would camp in the house until the siege was over, going home only to sleep.
"Concerning Sally"
William John Hopkins
An occasion such as I have mentioned arose on the day of the Hazens' fire, and Mrs. upJohn had accordingly sent John Junior around to Letty's house with the customary message.
"Concerning Sally"
William John Hopkins