Vaccina is a term that refers to the act of vaccinating or the substance used in vaccination, commonly known as a vaccine. Synonyms for vaccina include inoculation, immunization, prophylaxis, prevention, and defense. Inoculation and immunization both refer to the process of receiving a vaccine to develop immunity against a disease. Prophylaxis indicates a preventative measure taken to avoid infection, and prevention refers to the act of preventing an illness from occurring. Defense is a more general term that includes all measures taken to protect oneself from a potential threat. Vaccina and its synonyms remain crucial in the fight against infectious diseases and have been instrumental in preventing epidemics and pandemics throughout history.