Vioxx was a prescription drug that was used for pain relief and was removed from the market due to safety concerns. It was also known by its generic name, rofecoxib. Other synonyms for Vioxx include nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin, ibuprofen, and naproxen. These drugs work by reducing inflammation, swelling, and pain. However, long-term use of NSAIDs can lead to serious side effects, including stomach bleeding, kidney damage, and increased risk of heart attack and stroke. Therefore, it is important to use these drugs only as directed and to talk to a doctor if you have any concerns about their use.