The phrase "wert of significance" implies that something is important or noteworthy. There are several synonyms that can convey this meaning, such as "worthwhile," "meaningful," "substantial," "pertinent," or "significant." Each of these words implies that something is not only important but also has a valid and relevant reason for being so. For example, a medical breakthrough could be described as "significant" because it has valuable implications for human health. Similarly, a political decision could be called "pertinent" because it has a direct impact on people's daily lives. Regardless of the word chosen, when something is described as "wert of significance," it suggests that it deserves attention, consideration, and respect.