The phrase "what makes one tick" typically refers to the unique personality or characteristics that motivate an individual. Some synonyms for this phrase include "what drives someone," "what inspires someone," "what motivates someone," and "what fuels someone." Other related phrases include "what lights a fire under someone," "what ignites someone's passion," and "what gets someone going." These phrases all speak to the underlying factors that push someone forward and give them purpose. Understanding what makes a person tick can be helpful in building relationships, fostering teamwork, and inspiring personal growth and development.