There are numerous synonyms that can be used interchangeably with the phrase "with ease". Some of these synonyms include effortlessly, smoothly, easily, simply, comfortably, fluently, competently, naturally, breezily, leisurely, and without difficulty. All of these words convey the same sense of proficiency and dexterity in a given task or situation, with little or no struggle or tension. Whether it be in sports, academics, or any other activities, using the right synonym for "with ease" can add more variety to your language and help you communicate better and more effectively.