The phrase "with the best will in the world" means with the utmost effort and sincere intention to accomplish something. There are many synonyms for this phrase that convey the same meaning, including "with all sincerity," "with full determination," "with the utmost dedication," "with complete commitment," and "with wholehearted effort." These phrases all convey a sense of genuine desire to complete a task or achieve a goal, and they help to emphasize the importance of maintaining a positive attitude and putting in maximum effort. Using these synonyms in place of "with the best will in the world" can add depth and variety to your language, while still conveying the same essential meaning.