When it comes to being knowledgeable and skilled in a particular area, there are many different phrases and synonyms that can be used instead of "with the know-how." Some examples include "experienced," "proficient," "skilled," "competent," "seasoned," "adept," "talented," "practiced," "versed," "fluent," "qualified," "capable," and "expert." Each of these words conveys a slightly different shade of meaning, but all suggest a level of expertise and know-how that can only come from years of practice and experience. So if you want to convey a sense of confidence and proficiency in a certain field, there are plenty of alternative words and phrases at your disposal.