The phrase "with the throttle wide open" is often used to describe something that is moving or progressing at full speed or maximum effort. Some synonyms for this phrase include "at full tilt," "at full speed," "at full throttle," "pedal to the metal," and "full steam ahead." These phrases convey the idea of maximum speed and effort, whether in physical activity or in business or personal endeavors. They are also often used to indicate a sense of urgency or importance, and are commonly found in motivational or inspirational language. Overall, these synonyms for "with the throttle wide open" are powerful, dynamic expressions that convey energy and determination.