The phrase "work up on" means to develop or escalate something, usually a feeling or emotion, to a higher level. Some antonyms for "work up on" would include "calm down," "relax," "unwind," and "de-escalate." These words represent the opposite of working up on something, as they imply a decrease in intensity or excitement. For instance, if one is feeling anxious and overwhelmed, taking a break to relax can help in calming down the nerves. Similarly, if someone is feeling angry, it would be appropriate to de-escalate the situation by calming down their emotions. Antonyms for "work up on" can be useful in various contexts, from managing emotions to handling stressful situations effectively.