The word "worthless persons" denotes a sense of disdain and devaluation of others. If you are looking to express a similar sentiment, there are a few synonyms and alternatives you could use. One option is to use the word "good-for-nothing", which similarly connotes lack of value or usefulness. Another option is the phrase "dead weight," which indicates someone who is dragging a group down and not contributing to its overall success. You could also consider the phrase "time-waster," which suggests someone who is not productive or contributing to a particular task. Ultimately, the choice of synonym will depend on the context and tone of the intended message.