The Yazoo River is a significant waterway located in the southern region of the United States. There are several synonyms for the Yazoo River, including the Yazoo, the Yazous River, and the River of Death. The river is named after the Yazoo tribe, who were indigenous peoples that originally inhabited the area. It flows from the Mississippi River in the state of Louisiana, and runs through the state of Mississippi, before eventually emptying into the Gulf of Mexico. The Yazoo River is known for its abundant wildlife, rich history, and important role in the commerce and transportation of the region.