Yellow atrophy of the liver, also known as acute yellow atrophy or yellow hepatisation, is a rare condition that affects the liver. This life-threatening disease is characterized by the rapid destruction of liver cells, resulting in liver size reduction, yellow discoloration, and subsequent dysfunction. While there are no direct synonyms for this specific term, it can be referred to as fulminant hepatic failure or massive hepatic necrosis. These terms convey the severe nature of the disease where the liver deteriorates rapidly, leading to organ failure. It is important to seek immediate medical attention if any symptoms related to yellow atrophy of the liver are experienced, as timely interventions can be critical for a positive outcome.