"Yes'm" is a shortened form of "yes ma'am," which is a respectful and polite way of addressing a woman. As an interjection, it expresses agreement, assent, or acknowledgement. Antonyms or opposites of "yes'm" could include "no'm" or "no ma'am," which express disagreement, disapproval, or a lack of acknowledgement. However, using such phrases in a formal or polite context may be considered rude or disrespectful. Other possible antonyms could include words like "maybe," "uncertain," or "not sure," which convey hesitation, doubt, or indecisiveness, rather than a clear affirmation or negation.