The phrase "you and I" is a common way to refer to two people, but there are many synonyms that can be used to convey the same meaning. Some examples include "we," "us," "both," "together," "pair," "duo," and "couple." Each of these words can be used in different contexts depending on the tone and formality of the situation. For instance, "we" and "us" are generally more informal and conversational, while "pair" and "duo" are more formal and academic. Ultimately, the choice of synonym will depend on the intention of the speaker and how they want to be perceived by the listener.