Zinc finger nuclease (ZFN) is a specialized protein that has gained popularity in gene editing due to its ability to cut DNA at precise locations. However, there are many synonyms used to describe this molecule, such as ZFN endonuclease, zinc finger endonuclease, and zinc finger cutting enzyme. These terms all refer to the same protein that uses zinc fingers to recognize specific DNA sequences and nuclease activity to cleave the DNA at those sites. Other related terms include engineered nucleases, which can include both ZFNs and other gene editing tools like TALENs and CRISPR-Cas9. Regardless of the name, these tools have revolutionized the field of genetics by allowing researchers to manipulate DNA with precision and specificity.