Alagille Syndrome is a genetic disorder that affects the liver, heart, and other organs. It is also known as Alagille-Watson Syndrome, syndromic bile duct paucity, and arteriohepatic dysplasia. Other synonyms include hepatic ductular hypoplasia, hepatofugal portal flow defect, and paucity of interlobular bile ducts. The onset of symptoms can vary greatly, but common signs include jaundice, poor growth, and facial abnormalities. While there is currently no cure for Alagille Syndrome, treatments such as medications, surgery, and liver transplant can help manage the symptoms and improve quality of life. Early diagnosis and treatment are important for improving outcomes for those with Alagille Syndrome.