Anguish of mind is a poignant emotional state that is usually associated with feelings of distress, despair, and pain. It is a common human experience that can be caused by various situations such as loss, failure, or betrayal. Synonyms for anguish of mind include agony, misery, suffering, torment, sorrow, heartache, and pain. Each of these phrases denotes a state of intense emotional pain and distress that can be caused by various factors. While anguish of mind may be a difficult emotion to experience, it is important to seek support and help during such times to ensure healthy coping and resolution.