The word "anguine" is an adjective that refers to feeling or expressing anxiety or dread. Synonyms for anguine may include apprehensive, fearful, nervous, uneasy, worried, hesitant, edgy, jittery, and on edge. Other related words may include anxious, perturbed, agitated, panicky, and tense. These synonyms can be used interchangeably depending on the context. For example, one may feel anguine about an upcoming presentation, but they may also feel nervous, apprehensive, or uneasy. Similarly, one may appear anguine when discussing a difficult topic, but they may also appear agitated, anxious, or tense. Regardless of the words used, the sentiment conveyed is that of unease and discomfort.