Autocoid is a term used to describe substances that are produced locally in the body and act as chemical messengers within the body. Sometimes, it can be challenging to find an appropriate synonym for this term. However, some of the closest synonyms for autocoid may include local hormone, tissue factor, or mediator. Differentiated by the location, local hormones play a vital role in the regulation of various physiological processes, while tissue factors can stimulate various biological and cell signaling processes. Mediators, on the other hand, help to facilitate better communication between different cells within the body and regulate inflammation processes. Overall, these terms can be used interchangeably with autocoid in most cases.