The phrase "be affected with" means to have or experience some kind of condition or ailment. There are various synonyms that can be used instead of this phrase, such as "suffer from," "have," "contract," "acquire," or "develop." These synonyms convey the same idea, but with different shades of meaning. For example, "suffer from" implies a more chronic or ongoing condition, while "acquire" suggests a sudden or unexpected onset. Using synonyms can help add variety to your writing and prevent repetition, while still communicating the same essential message.