The word benefic refers to something that is good, helpful, or beneficial. As such, its antonyms are words that indicate the opposite. Some antonyms for benefic include harmful, hurtful, negative, maleficent, and malignant. Whereas benefic implies a positive impact, harmful implies a negative or undesirable impact. Hurtful suggests causing pain or injury. Negative is the opposite of positive, meaning unfavorable or pessimistic. Maleficent and malignant indicate wickedness, evil, or malice. Therefore, using antonyms for benefic is essential when trying to describe the opposite of something positive, such as a medical treatment, a decision, or a personality trait.