There are several alternative phrases that can be used as synonyms for "by its very nature." Some of these include "intrinsically," "inherently," "essentially," "naturally," and "by definition." Depending on the context and the emphasis that you want to place, each of these phrases can be used interchangeably with "by its very nature." For instance, if you want to highlight the innate qualities of something, you might use "inherently" or "intrinsically". Alternatively, if you want to emphasize that a characteristic is fundamental to the entity in question, "by definition" might be more effective. Regardless of which phrase you use, each of these synonyms helps to convey the same essential meaning of something being a fundamental or basic part of its nature.