C-OF-C is an acronym for the phrase "Chief of Staff". A Chief of Staff is a senior-level executive who acts as a key advisor to a company's or organization's leadership team. They are responsible for managing the day-to-day operations of the organization, coordinating activities with other departments and divisions, and providing strategic guidance on major decisions. Synonyms for the term "Chief of Staff" include General Manager, Executive Director, Manager, President, Vice President, Director, and Administrator. These titles all refer to individuals who hold significant authority within an organization, and who are tasked with overseeing its daily operations and long-term strategies.