Calabar-bean vine is a common name for the African plant Physostigma venenosum, which is known for its highly toxic seeds that contain the chemical physostigmine. Some synonyms for calabar-bean vine include Ordeal bean, Chop nut, Injection bean, and Esere. The name Ordeal bean comes from the practice of using the plant's seeds as a trial by ordeal in some African cultures. Injection bean refers to the use of the physostigmine extracted from the seeds as a treatment for glaucoma and other eye diseases. Chop nut and Esere are more commonly used in Nigeria, where the plant is traditionally used in local medicine.