Physostigma Venenosum is a plant species commonly known as the Calabar bean. It is a tropical legume that is highly poisonous and contains the alkaloids physostigmine, eseramine, and calabarine. The bean has been used for centuries in African traditional medicine for various healing treatments. Due to its toxicity, synonyms for the Physostigma Venenosum includes Strychnos physostigma, Physostigma venenosa, Ormosia calabarica, and Ministigma lanceolata. Despite the deadly effects of the bean, it has been employed in modern medicine as a therapeutic agent for treating glaucoma, myasthenia gravis, and other ailments. However, the use of the Calabar bean is still a risky venture and should only be administered in controlled doses by a qualified physician.