City-bred refers to someone who was raised or brought up in an urban area and has adapted to its lifestyle and culture. Some synonyms for city-bred are urbanized, citified, metropolitan, city-borne, and city-raised. These terms emphasize the individual's familiarity and experience with city life and their assimilation into its culture. On the other hand, words like rural, rustic, or provincial could be used as antonyms to describe someone who grew up in a small town or countryside, highlighting the differences in lifestyle and upbringing. Regardless of the terminology used, everyone's background shapes their attitude and approach to life, and city-bred individuals bring a unique perspective to any situation they find themselves in.