The word "co-mates" refers to people who share a common background or situation. The antonyms of co-mates are individuals who are unrelated, dissimilar, divergent, antagonistic, opposing, disagreeing, or contrasting in nature. Some antonyms for co-mates include strangers, enemies, adversaries, competitors, opponents, or foes. These words imply a lack of connection or commonality between individuals, which is opposite to the meaning of co-mates. While co-mates suggest unity and collaboration, its antonyms indicate isolation and resistance. Therefore, understanding the antonyms of a word assists in developing a clear understanding of its meaning and context.