The word "defiers" can be replaced with a variety of synonyms to convey a similar meaning or sentiment. These include "rebellious individuals," "insurgents," "dissenters," or "mavericks." Other options include "nonconformists," "revolutionaries," "mutineers," or "opponents." These words all signify a resistance or opposition to authority, rules, or conventional wisdom. Depending on the context, one of these synonyms may be more appropriate than the others. Nonetheless, they all capture the spirit of defiance and rebellion that the word "defiers" connotes.