Deoxygenate means to remove or reduce the oxygen content in something. There are several synonyms for deoxygenate, including anoxic, anaerobic, hypoxic, and oxygen-depleted. Anoxic refers to a complete lack of oxygen, while anaerobic implies an environment without oxygen. Hypoxic means a reduced level of oxygen, and oxygen-depleted implies a reduction in the oxygen level of a specific substance. Deoxygenate is commonly used in relation to water, where it refers to the removal of dissolved oxygen from the water. In such cases, aerate (add oxygen) is the antonym of deoxygenate. Other synonyms of deoxygenate include devitalize, deplete, and exhaust.