As you are aware, I have never been able to soothe myself with the sugary delusions of religion; for these things stand convicted of the utmost absurdity in light of modern scientific knowledge. With Nietzsche, I have been forced to confess that mankind as a whole has no goal or purpose whatsoever, but is a mere superfluous speck in the unfathomable vortices of infinity and eternity. Accordingly, I have hardly been able to experience anything which one could call real happiness; or to take as vital an interest in human affairs as can one who still retains the hallucination of a "great purpose" in the general plan of terrestrial life. … However, I have never permitted these circumstances to react upon my daily life; for it is obvious that although I have "nothing to live for", I certainly have just as much as any other of the insignificant bacteria called human beings. I have thus been content to observe the phenomena about me with something like objective interest, and to feel a certain tranquillity which comes from perfect acceptance of my place as an inconsequential atom. In ceasing to care about most things, I have likewise ceased to suffer in many ways. There is a real restfulness in the scientific conviction that nothing matters very much; that the only legitimate aim of humanity is to minimise acute suffering for the majority, and to derive whatever satisfaction is derivable from the exercise of the mind in the pursuit of truth.
H. P. Lovecraft